It is the largest district of Aydın in terms of population. It is more crowded than many provincial centers in our country. The Persians, who defeated the Lydians in 546 BC, dominated the region, and in 334 BC they were annexed to Macedonia by Alexander the Great. When the Seljuks came to Anatolia after the Roman and Byzantine periods, Nazilli and its environs were under the influence of the Turkish-Islamic civilization. After this period, various tribes of the Oghuz tribes settled in the region. Although it was attached to the Ottoman Empire in 1390, it later came under the sovereignty of Aydınoğulları Principality. In 1425, it was again subordinated to the Ottoman rule.
Because it was a shopping center during the Ottoman period, Pazarköy was later called Nazlıköy. While the district center was the village of Kestel, upon the development of Nazilli, the center became Nazilli in 1831. The Weaving Factory was established in Nazilli, which was opened by Atatürk in 1937; It ensured the rapid development of this segment and industry. The agriculture in the region was also affected by the factory, and cotton production was put on a scientific basis and significant increases in production were achieved. Agriculture is very important due to its transportation facilities and fertile lands.
The district with the highest industrialization rate and the most developed in industry after Aydın city center is Nazilli. Hand weaving in the past is almost non-existent today. In recent years, poultry, egg breeding, strawberries and greenhouses have entered into an important development process.